High Performance Liquid Chromatography (HPLC)/ Ultra-High Performance Liquid Chromatography (UPLC)/ Size Exclusion Chromatography (SEC)/ Gel Permeation Chromatography (GPC)/ Capillary Electrophoresis (CE)*
Equipment: Thermo Fisher TSQ
Working Principle
- Liquids (Mobile Phase) are pumped through a column to a detector
- Depending on choice of column, different sizes, polarity, viscosity,
molecular weights can be separated
by retention time to the detector
- Analysis focuses on contents of the mobile phase
Technical Information
- Information on composition in mobile phase
- Molecular weights of liquids
- Size of particles in a liquid
- Molecule size distribution
- Molecule charge distribution
- Quality control tool for chemical, pharmaceutical and food industries
Detection of Adjuvants in Vaccines
- Adjuvants increase host's immune
systems when the
vaccines are
administered
- Different detectors can better resolve
the Adjuvants in the
vaccines such as
charged aerosol
versus UV